Aiming at the difference of health system resilience in urban areas and the random evolution of demand for emergency medical supplies， a multi-stage dynamic allocation model for emergency medical supplies based on resilience assessment was proposed. Firstly， combined with the entropy method and the K-means algorithm， the resilience assessment system and classification method of area’s health system were established. Secondly， the random evolution characteristic of demand state was designed as a Markov process， and triangular fuzzy numbers were used to deal with the fuzzy demand， thereby constructing a multi-stage dynamic allocation model of emergency medical supplies. Finally， the proposed model was solved by the binary Artificial Bee Colony （ABC） algorithm， and the effectiveness of the model was analyzed and verified by an actual example. Experimental results show that the proposed model can realize the dynamic allocation of supplies to stabilize the demand changes and prioritize the allocation of areas with weak resilience， reflecting the fairness and efficiency of emergency management requirements.